SLC25A28
Description
The SLC25A28 (solute carrier family 25 member 28) is a protein-coding gene located on chromosome 10.
SLC25A28 is a mitochondrial iron transporter that facilitates the uptake of iron into mitochondria. This function is likely crucial for the synthesis of heme in hemoproteins and the assembly of iron-sulfur clusters in non-erythroid cells.
SLC25A28 is also known as MFRN2, MRS3/4, MRS4L, NPD016.
Associated Diseases
- colorectal cancer
- digestive system cancer
- diverticulitis
- Lisch epithelial corneal dystrophy
- X-linked endothelial corneal dystrophy
- X-linked corneal dermoid
- autosomal dominant keratitis
- Schnyder corneal dystrophy
- male infertility with teratozoospermia due to single gene mutation
- lattice corneal dystrophy type I
- granular corneal dystrophy type I
- corneal dystrophy, punctiform and polychromatic pre-descemet
- isolated ectopia lentis
