SLC25A11

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Description

The SLC25A11 (solute carrier family 25 member 11) is a protein-coding gene located on chromosome 17.

SLC25A11, encoding the mitochondrial 2-oxoglutarate/malate carrier protein, is a human gene. Inactivating mutations within this gene are linked to an increased predisposition towards metastatic paraganglioma.

SLC25A11 is also known as OGC, PGL6, PPGL6, SLC20A4.

Associated Diseases

• Hereditary pheochromocytoma-paraganglioma
• Paragangliomas 6