SERPINB9
Description
The SERPINB9 (serpin family B member 9) is a protein-coding gene located on chromosome 6.
Serpin B9 is a protein encoded by the SERPINB9 gene in humans. It belongs to the serpin family of proteins, which are known to bind and inactivate serine proteinases. These interactions are involved in various cellular processes such as coagulation, fibrinolysis, complement fixation, matrix remodeling, and apoptosis.
Inhibits the activity of Granzyme B, a serine protease.
SERPINB9 is also known as CAP-3, CAP3, PI-9, PI9.
Associated Diseases
- cancer
- skin squamous cell carcinoma
- isolated agammaglobulinemia
- severe combined immunodeficiency due to CTPS1 deficiency
- immunodeficiency 18
- severe combined immunodeficiency due to CARD11 deficiency
