SCGN


Description

The SCGN (secretagogin, EF-hand calcium binding protein) is a protein-coding gene located on chromosome 6.

Secretagogin is a protein that in humans is encoded by the SCGN gene. The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in potassium chloride-stimulated calcium flux and cell proliferation. This protein plays an important role in the release of the stress hormone Corticotropin-releasing hormone (CRH) and which only then enables stress processes in the brain.

SCGN is also known as CALBL, DJ501N12.8, SECRET, SEGN, setagin.

Associated Diseases



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