RRM2
Description
The RRM2 (ribonucleotide reductase regulatory subunit M2) is a protein-coding gene located on chromosome 2.
RRM2 (Ribonucleoside-diphosphate reductase subunit M2) is an enzyme encoded by the RRM2 gene in humans. It forms a complex with another protein to create ribonucleotide reductase, which catalyzes the conversion of ribonucleotides into deoxyribonucleotides, essential for DNA synthesis. RRM2 production is tightly controlled by the cell cycle. The gene has alternative promoters, leading to two isoforms with different N-termini.
RRM2 is crucial for DNA synthesis, providing the necessary building blocks by catalyzing the conversion of ribonucleotides into deoxyribonucleotides. It also plays a role in regulating cellular processes by inhibiting Wnt signaling.
RRM2 is also known as C2orf48, R2, RR2, RR2M.
