RPS5
Description
The RPS5 (ribosomal protein S5) is a protein-coding gene located on chromosome 19.
RPS5 may refer to the human gene RPS5, which encodes a protein called 40S ribosomal protein S5.
RPS5 is a component of the small ribosomal subunit, which is essential for protein synthesis in the cell. It is also part of the small subunit (SSU) processome, the first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, RPS5 and other ribosome biogenesis factors, an RNA chaperone, and ribosomal proteins work together to fold, modify, rearrange, and cleave the nascent pre-rRNA. They also participate in the targeted degradation of pre-ribosomal RNA by the RNA exosome.
RPS5 is also known as S5, uS7.
Associated Diseases
- Duchenne muscular dystrophy
- cystic fibrosis
- COVID-19
- Becker muscular dystrophy
- qualitative or quantitative defects of dystrophin
- aniridia
- hemophilia B
- hemophilia A
- cystinosis
- Alport syndrome
