RPS15
Description
The RPS15 (ribosomal protein S15) is a protein-coding gene located on chromosome 19.
The RPS15 gene encodes a protein that is part of the 40S ribosomal subunit, which is one of the two subunits that make up ribosomes. Ribosomes are essential for protein synthesis. This protein belongs to the S19P family of ribosomal proteins and is located in the cytoplasm. The RPS15 gene has been linked to the activation of several types of tumors, including insulinomas, esophageal cancers, and colon cancers. Similar to other genes encoding ribosomal proteins, there are multiple inactive copies of this gene scattered throughout the genome.
This protein is a component of the small ribosomal subunit, which is a key part of the ribosome. The ribosome is a large complex of RNA and proteins that synthesizes proteins within the cell.
RPS15 is also known as RIG, S15, uS19.
Associated Diseases
- Duchenne muscular dystrophy
- cystic fibrosis
- COVID-19
- Diamond-Blackfan anemia
- Becker muscular dystrophy
- qualitative or quantitative defects of dystrophin
- aniridia
- hemophilia B
- cystinosis
- hemophilia A
- Alport syndrome
