RPL39
Description
The RPL39 (ribosomal protein L39) is a protein-coding gene located on chromosome X.
60S ribosomal protein L39 is a protein encoded by the RPL39 gene in humans. Ribosomes, the organelles that synthesize proteins, are composed of a small 40S subunit and a large 60S subunit. This gene encodes a ribosomal protein that is part of the 60S subunit. The protein belongs to the S39E family of ribosomal proteins and is located in the cytoplasm. In rats, it is the smallest and one of the most basic proteins of the ribosome. This gene is co-transcribed with the U69 small nucleolar RNA gene, which is located in its second intron. There are multiple processed pseudogenes of this gene dispersed throughout the genome.
RNA-binding component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
RPL39 is also known as L39, RPL39P42, RPL39_23_1806, eL39.
Associated Diseases
- Duchenne muscular dystrophy
- cystic fibrosis
- Becker muscular dystrophy
- endometrial cancer
- qualitative or quantitative defects of dystrophin
- aniridia
- cystinosis
- hemophilia A
- Alport syndrome
- hemophilia B
- cancer
- pachyonychia congenita
