RPAIN

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Description

The RPAIN (RPA interacting protein) is a protein-coding gene located on chromosome 17.

RPAIN is a human gene that encodes the RPA-interacting protein.

RPAIN, also known as hRIP, facilitates the transport of the RPA complex into the nucleus, possibly through interactions with importin beta. Isoform 2 undergoes sumoylation and plays a role in directing the RPA complex to the PML body within the nucleus. This localization contributes to the RPA complex's involvement in DNA metabolism.

RPAIN is also known as HRIP, RIP.

Associated Diseases