RLN1
Description
The RLN1 (relaxin 1) is a protein-coding gene located on chromosome 9.
Relaxin, produced by the ovaries, works alongside estrogen to widen the birth canal in numerous mammals. It may also play a role in reshaping connective tissues during pregnancy, contributing to the expansion of pubic ligaments and the softening of the cervix.
RLN1 is also known as H1, H1RLX, RLXH1, bA12D24.3.1, bA12D24.3.2.
Associated Diseases
- low grade glioma
- Kallmann syndrome
- partial androgen insensitivity syndrome
- 46,XY disorder of sex development due to 17-beta-hydroxysteroid dehydrogenase 3 deficiency
- ring chromosome Y
- isochromosomy Yp
- Leydig cell hypoplasia
- Kennedy disease
- isochromosomy Yq
- hypogonadotropic hypogonadism
- partial chromosome Y deletion
- familial male-limited precocious puberty
- 46,XY partial gonadal dysgenesis
- spermatogenic failure 25
- spermatogenic failures 50
- breasts and/or nipples, aplasia or hypoplasia of, 2
