RAP2A
Description
The RAP2A (RAP2A, member of RAS oncogene family) is a protein-coding gene located on chromosome 13.
Ras-related protein Rap-2a is a protein that in humans is encoded by the RAP2A gene. RAP2A is a member of the Ras-related protein family.
RAP2A is a small GTP-binding protein that cycles between an inactive GDP-bound state and an active GTP-bound state. In its active form, it interacts with and regulates several effectors, including MAP4K4, MINK1, and TNIK. RAP2A is part of a signaling complex composed of NEDD4, RAP2A, and TNIK, which regulates neuronal dendrite extension and arborization during development. More broadly, RAP2A participates in various signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion, and cell spreading.
RAP2A is also known as K-REV, KREV, RAP2, RbBP-30.
