RAB26
Description
The RAB26 (RAB26, member RAS oncogene family) is a protein-coding gene located on chromosome 16.
RAB26 is a human gene that encodes the Ras-related protein Rab-26, a key regulator of intracellular membrane trafficking.
Rab proteins are key regulators of intracellular membrane trafficking, controlling the formation and fusion of transport vesicles. They switch between inactive (GDP-bound) and active (GTP-bound) states, recruiting different effectors to membranes for vesicle formation, movement, tethering, and fusion. RAB26 specifically mediates the transport of ADRA2A and ADRA2B from the Golgi apparatus to the cell membrane. It also plays a role in the maturation of zymogenic granules and pepsinogen secretion in the stomach, as well as amylase secretion from acinar granules in the parotid gland.
RAB26 is also known as V46133.
