PSMD6
Description
The PSMD6 (proteasome 26S subunit, non-ATPase 6) is a protein-coding gene located on chromosome 3.
PSMD6 (26S proteasome non-ATPase regulatory subunit 6) is an enzyme involved in protein degradation. It's part of the proteasome, a complex that plays a vital role in maintaining the health and proper function of cells by breaking down damaged or unnecessary proteins. This process is essential for many cellular functions, including cell division, programmed cell death, and DNA repair. A malfunctioning proteasome can contribute to various diseases, including neurodegenerative disorders, cardiovascular diseases, inflammatory responses, and autoimmune diseases. Researchers are exploring the potential of targeting the proteasome for therapeutic interventions in these conditions.
PSMD6, also known as RPN7, is a subunit of the 26S proteasome, a large protein complex responsible for breaking down proteins tagged with ubiquitin. This process is crucial for maintaining cellular function by removing damaged or misfolded proteins and regulating the levels of proteins needed for various cellular processes. The 26S proteasome is involved in a wide range of cellular activities, including cell division, programmed cell death (apoptosis), and DNA repair.
PSMD6 is also known as Rpn7, S10, SGA-113M, p42A, p44S10.
