PRMT3


Description

The PRMT3 (protein arginine methyltransferase 3) is a protein-coding gene located on chromosome 11.

PRMT3 is a human gene that encodes the enzyme protein arginine N-methyltransferase 3. This enzyme is responsible for methylating arginine residues in target proteins. PRMT3 has been shown to interact with RPS2.

PRMT3 is a protein-arginine N-methyltransferase that catalyzes both monomethylation and asymmetric dimethylation of arginine residues in target proteins, classifying it as a type I methyltransferase. It may regulate retinoic acid synthesis and signaling by inhibiting the activity of ALDH1A1 retinal dehydrogenase.

PRMT3 is also known as HRMT1L3.

Associated Diseases


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