SYCP3
Description
The SYCP3 gene encodes a protein crucial for the formation of the synaptonemal complex (SC), a protein structure essential for proper chromosome pairing and recombination during meiosis. Meiosis is a specialized cell division process that produces gametes (sperm and egg cells), ensuring genetic diversity in offspring. The SC acts as a scaffold, holding homologous chromosomes together, facilitating genetic exchange between them. Defects in SYCP3 function can disrupt this process, leading to infertility in males.
Associated Diseases
- Male infertility
- Spermatogenic failure-4
- Azoospermia (absence of sperm in semen)
- Oligospermia (low sperm count)
- Asthenozoospermia (poor sperm motility)
Did you know?
Mutations in the SYCP3 gene are one of the most common causes of male infertility due to meiotic defects.
