ZP2
Description
ZP2, or Zona Pellucida glycoprotein 2, is a crucial protein involved in mammalian fertilization. It forms part of the zona pellucida, a thick, glycoprotein layer surrounding the oocyte (egg cell). ZP2 plays a vital role in sperm binding and acrosome reaction, ensuring the successful fertilization process. Its intricate structure and interactions with other zona pellucida proteins make it an essential component for reproductive success.
Associated Diseases
- Infertility: Mutations in the ZP2 gene can lead to infertility in both males and females due to impaired sperm binding and fertilization.
- Premature Ovarian Failure: Some studies suggest a possible link between ZP2 gene variations and premature ovarian failure.
Did you know?
ZP2 is a highly conserved protein, with similar structures found across different mammalian species, highlighting its fundamental role in fertilization.
