ZC3H14

Description

The ZC3H14 gene, located on chromosome 19, encodes a protein known as zinc finger CCCH-type containing 14. This protein plays a critical role in RNA metabolism, specifically in the process of RNA splicing. ZC3H14 is involved in regulating the splicing of various mRNAs, including those involved in cell growth, differentiation, and immune function. It also interacts with other proteins involved in RNA processing and translation. Disruptions in the function of ZC3H14 can lead to a range of health issues.

Associated Diseases

• Myelodysplastic syndromes (MDS)
• Acute myeloid leukemia (AML)
• Neurodevelopmental disorders
• Immune deficiencies

Did you know?

ZC3H14 has been linked to the regulation of microRNAs, which are small non-coding RNAs that play a crucial role in gene expression.