TTC29

Description

The TTC29 gene, located on chromosome 16, encodes a protein known as tetratricopeptide repeat domain 29. This protein plays a crucial role in various cellular processes, including protein trafficking, microtubule organization, and DNA repair. TTC29 interacts with other proteins to form complexes that regulate these critical functions. Mutations in the TTC29 gene can disrupt these interactions, leading to a range of health issues. Understanding the role of TTC29 is essential for developing new therapies for diseases associated with its dysfunction.

Associated Diseases

• Spinocerebellar Ataxia 36 (SCA36)
• Hereditary Spastic Paraplegia (HSP)
• Intellectual Disability
• Neurodevelopmental Disorders

Did you know?

TTC29 protein has a unique structure with multiple tetratricopeptide repeat (TPR) domains, which allow it to interact with a wide variety of other proteins.