TRAPPC4
Description
TRAPPC4, also known as Trafficking Protein Particle Complex Subunit 4, is a vital component of the TRAPP complex. This protein complex is essential for the movement of vesicles, tiny sacs that transport molecules within cells. TRAPPC4 plays a crucial role in the formation and function of these vesicles, particularly those involved in the secretory pathway. This pathway is responsible for transporting proteins from the endoplasmic reticulum to the Golgi apparatus and ultimately to their final destinations. Disruptions in the function of TRAPPC4 can lead to various cellular defects, impacting processes like protein secretion, cellular signaling, and overall cellular homeostasis.
Associated Diseases
- Coatomer protein complex subunit alpha (COPA) syndrome
- Neurodevelopmental disorders
- Congenital disorders of glycosylation (CDG)
- Lysosomal storage diseases
Did you know?
Mutations in the TRAPPC4 gene have been linked to specific types of cancer, highlighting the crucial role this gene plays in normal cellular growth and development.
