TFG
Description
The TFG gene encodes a protein called TFG, a crucial component of the cell signaling pathways that regulate cellular growth, development, and response to various stimuli. TFG acts as a guanine nucleotide exchange factor (GEF) for the small GTPase RhoA, playing a critical role in activating RhoA signaling. This pathway is involved in diverse cellular processes, including cytoskeletal reorganization, cell migration, and gene expression. Mutations in TFG have been linked to a range of developmental and disease states, highlighting the importance of this gene in maintaining cellular homeostasis.
Associated Diseases
Did you know?
TFG is a highly conserved gene across different species, indicating its fundamental role in cellular function.