TEX14

Description

TEX14, short for Testis Expressed 14, is a gene crucial for male fertility. It encodes a protein involved in the complex process of spermatogenesis, the production of sperm. This protein interacts with other proteins, playing a role in the formation of the acrosome, a cap-like structure on the sperm head essential for fertilization. Mutations in the TEX14 gene can disrupt these vital functions, leading to male infertility. Understanding the role of TEX14 in spermatogenesis is essential for developing novel treatments and diagnostic tools for male infertility.

Associated Diseases

• Male infertility
• Azoospermia (absence of sperm)
• Oligozoospermia (low sperm count)
• Asthenozoospermia (poor sperm motility)

Did you know?

Mutations in TEX14 can lead to a specific type of male infertility called globozoospermia, characterized by the absence of acrosomes in sperm.