SPATA16

Description

SPATA16 (Spermatogenesis Associated 16) is a gene located on chromosome 19 in humans. It encodes a protein that plays a crucial role in spermatogenesis, the process of sperm cell development. The SPATA16 protein is primarily expressed in the testes and is believed to be involved in several aspects of sperm formation, including flagellar assembly and motility. Mutations in the SPATA16 gene can lead to various male reproductive disorders, highlighting its importance in male fertility.

Associated Diseases

• Male infertility
• Asthenozoospermia (reduced sperm motility)
• Teratozoospermia (abnormal sperm morphology)
• Azoospermia (absence of sperm)

Did you know?

Mutations in the SPATA16 gene are more commonly found in men with severe male infertility, suggesting a strong correlation between the gene and reproductive health.