SNX10


Description

The SNX10 (sorting nexin 10) is a protein-coding gene located on chromosome 7.

SNX10 is a phosphoinositide-binding protein that participates in protein sorting and membrane trafficking within endosomes. It plays a crucial role in cilium biogenesis by regulating the transport and localization of proteins to the cilium. SNX10 is essential for the localization of V-ATPase subunits ATP6V1D and ATP6V0D1, and RAB8A to the cilium. This protein is also involved in osteoclast differentiation, ultimately contributing to bone resorption.

SNX10 is also known as OPTB8.

Associated Diseases


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