NOS1AP


Description

The NOS1AP gene, also known as CAPON, encodes a protein that plays a crucial role in regulating nitric oxide (NO) signaling pathways. NO is a signaling molecule involved in various physiological processes, including blood pressure regulation, immune response, and neuronal function. NOS1AP interacts with neuronal nitric oxide synthase (nNOS), the enzyme responsible for NO production, and modulates its activity. This interaction influences the release of NO and consequently affects downstream signaling pathways. Variations in the NOS1AP gene have been linked to several diseases and conditions, highlighting its importance in maintaining cellular homeostasis.

Associated Diseases

Did you know?

NOS1AP was initially identified as a protein that binds to the carboxyl-terminal domain of nNOS, hence its name, CAPON (carboxyl-terminal PDZ ligand of nNOS).


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