NDUFA11
Description
NDUFA11 is a gene that encodes a subunit of the NADH dehydrogenase (ubiquinone) complex, a crucial component of the electron transport chain within mitochondria. This chain plays a vital role in cellular respiration, the process by which cells convert food into energy. NDUFA11 is essential for the proper assembly and function of the complex, ensuring efficient energy production. Mutations in the NDUFA11 gene can disrupt this process, leading to a range of health issues.
Associated Diseases
- Leigh syndrome
- Mitochondrial Complex I Deficiency
- Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS)
- Neurodegenerative disorders
Did you know?
NDUFA11 is located on chromosome 1, a large chromosome containing numerous genes crucial for human development and function.
