NAT8L
Description
NAT8L, also known as N-alpha-acetyltransferase 8-like, is a vital enzyme involved in protein acetylation, a crucial post-translational modification impacting protein stability, activity, and localization. NAT8L specifically targets the N-terminal residue of proteins, adding an acetyl group to the alpha-amino group. This process, termed N-terminal acetylation, plays a multifaceted role in regulating a wide range of cellular processes, including protein folding, trafficking, and interaction with other molecules. Aberrant NAT8L function has been implicated in various diseases, highlighting its critical role in maintaining cellular homeostasis.
Associated Diseases
Did you know?
NAT8L is one of the most abundant enzymes in the human body, reflecting its widespread role in protein modification.
