MRM2
Description
The MRM2 gene, encodes a protein known as mitochondrial ribosomal protein L2. This protein is a critical component of the mitochondrial ribosome, the cellular machinery responsible for synthesizing proteins essential for mitochondrial respiration and energy production. MRM2 is highly conserved across species, highlighting its fundamental role in cellular metabolism. Its dysfunction can lead to a cascade of mitochondrial abnormalities, impacting various cellular processes and contributing to a range of diseases.
Associated Diseases
- Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-like Episodes (MELAS)
- Leigh Syndrome
- Diabetes Mellitus
- Neurodegenerative Disorders (e.g., Parkinson‘s Disease, Alzheimer‘s Disease)
Did you know?
Mutations in the MRM2 gene are associated with a range of clinical presentations, highlighting the gene‘s importance in maintaining mitochondrial health.
