KYNU
Description
The KYNU gene encodes the enzyme kynureninase, a crucial component in the kynurenine pathway, a metabolic route that breaks down tryptophan. This pathway generates various metabolites with diverse biological roles, including neurotransmitters, immunomodulators, and antioxidants. KYNU‘s role in this pathway is vital for maintaining proper brain function, immune response, and overall health. Variations in the KYNU gene have been linked to several neurological and immune disorders, emphasizing its importance in human health.
Associated Diseases
- Schizophrenia
- Bipolar disorder
- Major depressive disorder
- Alzheimer‘s disease
- Parkinson‘s disease
- Multiple sclerosis
- Systemic lupus erythematosus
- Cancer
Did you know?
Kynureninase activity is influenced by vitamin B6, making it a potential target for nutritional interventions in diseases linked to KYNU gene variations.
