HYAL1
Description
The HYAL1 gene encodes hyaluronidase 1, a crucial enzyme involved in the breakdown of hyaluronic acid (HA), a major component of the extracellular matrix. Hyaluronidase 1 plays a significant role in various physiological processes, including tissue remodeling, inflammation, and cell migration. Its activity is tightly regulated, and dysregulation can lead to pathological conditions.
Associated Diseases
- Cancer (e.g., breast, prostate, and ovarian cancer)
- Inflammatory diseases (e.g., rheumatoid arthritis, osteoarthritis)
- Reproductive disorders (e.g., endometriosis, infertility)
- Wound healing complications
- Viral infections (e.g., HIV, influenza)
- Neurological disorders (e.g., Alzheimer‘s disease)
Did you know?
Hyaluronidase is also known as the "spreading factor" because of its ability to increase the permeability of tissues, allowing for the spread of fluids and cells.
