GLS
Description
The GLS (glutaminase) is a protein-coding gene located on chromosome 2.
GLS, short for Glutaminase, is a gene and enzyme that plays a critical role in the human body. It is also used in other contexts, including as an abbreviation for various scientific, organizational, and geographical entities.
GLS (Glutaminase kidney isoform, mitochondrial) catalyzes the initial step in the primary pathway for glutamine breakdown in the kidneys. It contributes to maintaining acid-base balance in the body. GLS also regulates levels of glutamate, a key excitatory neurotransmitter in the brain.
GLS is also known as AAD20, CASGID, DEE71, EIEE71, GAC, GAM, GDPAG, GLS1, KGA.
Associated Diseases
- Epileptic encephalopathy, early infantile, 71
- Infantile cataract, skin abnormalities, glutamate excess, and impaired intellectual development
- Global developmental delay, progressive ataxia, and elevated glutamine
