FSHB
Description
The FSHB gene, located on chromosome 11, encodes the beta subunit of follicle-stimulating hormone (FSH). FSH is a crucial gonadotropin hormone produced by the pituitary gland, playing a vital role in both male and female reproductive function. In women, FSH stimulates follicle growth and estrogen production in the ovaries, ultimately leading to ovulation. In men, FSH promotes sperm production in the testes. Mutations in the FSHB gene can lead to various reproductive disorders, impacting fertility and hormone levels. Understanding the intricate role of FSHB is crucial for diagnosing and managing these conditions.
Associated Diseases
- Hypogonadotropic hypogonadism
- Infertility
- Ovarian insufficiency
- Premature ovarian failure
- Kallmann syndrome
Did you know?
FSHB gene mutations are relatively rare, affecting less than 1% of the population.
