FAM149B1
Description
The FAM149B1 (family with sequence similarity 149 member B1) is a protein-coding gene located on chromosome 10.
FAM149B1 (also known as KIAA0974) is an uncharacterized protein located in the nucleus of the cell. It contains multiple alpha-helices and a few beta-sheet structures in its predicted secondary structure. The gene is conserved across various species, including mammals, birds, reptiles, fish, and some invertebrates. The protein contains a DUF3719 domain, which is conserved across its orthologues. It is expressed at slightly below average levels in most human tissues, with high expression in brain, kidney, and testes tissues, while showing relatively low expression levels in pancreas tissues. The gene is located on chromosome 10 (10q22.2) and spans 3149 base pairs, including 5' and 3' UTR. It has 14 exons and is flanked by NUDT13 and DNAJC9-AS1.
FAM149B1 is also known as JBTS36, KIAA0974.