DNHD1

Description

DNHD1 (Deoxyribonuclease 1-Like, Homolog of) is a gene encoding a protein involved in DNA repair and neurological function. It plays a crucial role in the double-strand break repair pathway, helping to maintain genomic stability. DNHD1 interacts with other proteins involved in DNA repair, such as MRE11 and RAD50, forming a complex that processes DNA damage. Additionally, studies suggest that DNHD1 may contribute to neuronal development and function, with potential implications for neurodevelopmental disorders.

Associated Diseases

• Neurodevelopmental disorders
• Intellectual disability
• Autism spectrum disorder
• Cancer (specifically, breast cancer)
• Ataxia-telangiectasia-like disorder

Did you know?

Mutations in DNHD1 have been linked to a rare neurological disorder resembling Ataxia-telangiectasia, suggesting a crucial role in maintaining DNA integrity and neurological function.