DCXR : dicarbonyl and L-xylulose reductase
Description
The DCXR gene, located on chromosome 11, encodes a protein called DNA cross-link repair (DCXR). This protein plays a crucial role in the intricate cellular process of repairing damaged DNA, specifically focusing on interstrand cross-links (ICLs). ICLs are a type of DNA damage that can be caused by various factors, including exposure to certain chemicals and radiation. DCXR acts as a crucial component within a complex repair machinery, effectively removing these harmful ICLs from the DNA. This repair process is essential for maintaining the integrity of the genome and preventing the development of mutations that can lead to cancer. Given its vital role in DNA repair, the DCXR gene has garnered significant research interest, particularly in the context of understanding and potentially treating various cancers.
Associated Diseases
Did you know?
DCXR is a highly conserved protein, meaning its structure and function are similar across different species, highlighting its importance in maintaining life.
