CYP19A1 : cytochrome P450 family 19 subfamily A member 1

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Description

The CYP19A1 gene, also known as aromatase, plays a crucial role in the synthesis of estrogens, the primary female sex hormones. This gene encodes an enzyme that catalyzes the conversion of androgens, such as testosterone, into estrogens, including estradiol and estrone. Estrogens are vital for female development, reproduction, and overall health. They influence a wide range of physiological processes, including the development of secondary sexual characteristics, regulation of the menstrual cycle, bone health, and cardiovascular function. The CYP19A1 gene is highly regulated and its expression is influenced by various factors, including hormones, age, and environmental factors.

Associated Diseases

• Polycystic Ovary Syndrome (PCOS)
• Endometriosis
• Breast Cancer
• Uterine Fibroids
• Precocious Puberty
• Hypogonadism
• Osteoporosis
• Cardiovascular Disease

Did you know?

The CYP19A1 gene is one of the few genes that is expressed in both males and females, although its expression is significantly higher in females.