CPE
Description
The CPE gene, encoding carboxypeptidase E, is a critical component of the cellular machinery that processes and regulates peptides, including hormones and neuropeptides. CPE plays a crucial role in the endocrine and nervous systems, influencing a wide range of physiological functions. Its actions involve cleaving peptide precursors into their active forms, ensuring proper signal transduction, and regulating their stability and release. Genetic variations in the CPE gene have been implicated in several human diseases, highlighting its significance in maintaining cellular homeostasis.
Associated Diseases
- Obesity
- Type 2 Diabetes
- Neurodevelopmental disorders
- Alzheimer's disease
- Parkinson's disease
- Schizophrenia
- Cancer
Did you know?
Mutations in the CPE gene can lead to an accumulation of inactive pro-hormones, affecting the normal functioning of the endocrine system.
