CFL2


Description

CFL2, also known as cofilin-2, is a ubiquitous actin-binding protein playing a crucial role in regulating actin filament dynamics. CFL2 binds to actin filaments, promoting their depolymerization and facilitating the turnover of the actin cytoskeleton. This process is essential for various cellular functions, including cell migration, division, and intracellular transport. CFL2 activity is tightly regulated by phosphorylation, with its dephosphorylated form being active in promoting actin depolymerization.

Associated Diseases

Did you know?

CFL2 has been shown to be involved in the formation of filopodia, slender, finger-like projections on the cell surface that are essential for cell motility and sensing the environment.


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