CEACAM16
Description
The CEACAM16 (CEA cell adhesion molecule 16, tectorial membrane component) is a protein-coding gene located on chromosome 19.
Carcinoembryonic antigen-related cell adhesion molecule 16 is encoded in the human by the CEACAM16 gene. It is a member of the carcinoembryonic antigen family, a cluster of genes on chromosome 19. CEACAM16 is a structure of the tectorial membrane involved in hearing at low and high frequencies. It is the only carcinoembryonic antigen found in the platypus. The protein is expressed in mammalian outer hair cells, and mutations in this gene are associated with autosomal dominant nonsyndromic deafness.
Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane. {ECO:0000269|PubMed:21368133, ECO:0000269|PubMed:25589040, ECO:0000269|PubMed:29703829}
CEACAM16 is also known as CEAL2, DFNA4B, DFNB113.
