CDK6

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Description

CDK6, or Cyclin-Dependent Kinase 6, is a crucial protein kinase involved in the regulation of the cell cycle. It plays a pivotal role in the G1 phase, ensuring the cell progresses through this phase and commits to division. CDK6 forms a complex with cyclin D, activating downstream signaling pathways that control the expression of genes essential for DNA replication. This complex is tightly regulated, ensuring proper cell cycle control and preventing uncontrolled cell proliferation.

Associated Diseases

• Cancer (e.g., breast cancer, melanoma, leukemia)
• Neurological disorders (e.g., Alzheimer‘s disease)
• Developmental defects

Did you know?

Mutations in the CDK6 gene can lead to an increased risk of certain types of cancer.