CABP4

Description

The CABP4 gene, also known as calbindin-D28K, encodes a calcium-binding protein that plays a crucial role in maintaining calcium homeostasis within cells. This protein is primarily found in the brain, particularly in neurons, where it acts as a calcium buffer, preventing excessive calcium accumulation that can lead to cell damage. CABP4 is also expressed in other tissues, including the intestines, kidneys, and pancreas, suggesting its involvement in various physiological processes.

Associated Diseases

• Hypocalcemia
• Neurological disorders (e.g., epilepsy, Parkinson‘s disease)
• Cancer (e.g., breast cancer, prostate cancer)
• Osteoporosis

Did you know?

CABP4 is highly expressed in the cerebellum, a brain region crucial for motor coordination and learning.