BTG4
Description
BTG4, also known as B-cell translocation gene 4, is a gene that encodes a protein involved in various cellular processes, primarily cell cycle regulation. Its expression is tightly controlled and plays a critical role in mediating cell growth, differentiation, and apoptosis. BTG4 exerts its influence by interacting with key cell cycle regulators, including cyclin-dependent kinases (CDKs) and their inhibitors, ultimately modulating the progression of the cell cycle. Furthermore, BTG4 has been implicated in diverse cellular pathways, underscoring its multifaceted nature and potential significance in human health.
Associated Diseases
- Cancer (various types, including leukemia, lymphoma, and breast cancer)
- Neurological disorders (e.g., Alzheimer‘s disease, Parkinson‘s disease)
- Cardiovascular diseases (e.g., heart failure)
- Inflammatory conditions
Did you know?
BTG4 was initially discovered through its association with chromosomal translocations in B-cell leukemia, highlighting its potential role in cancer development.
