AVP : arginine vasopressin

Description

The AVP (arginine vasopressin) is a protein-coding gene located on chromosome 20.

The AVP gene provides instructions for making arginine vasopressin (AVP), also known as antidiuretic hormone (ADH). AVP begins as a larger molecule called a preprohormone, which is cleaved and modified to produce the active hormone and related proteins. The preprohormone is produced in the hypothalamus and transported to the pituitary gland, where active AVP is stored until needed. AVP's main function is regulating the body's water balance by controlling urine output. When fluid intake is low or fluid is lost (e.g., through sweating), the pituitary gland releases more AVP into the bloodstream. This high level of AVP signals the kidneys to reabsorb more water and produce less urine. When fluid intake is adequate, the pituitary gland releases less AVP.

Neurophysin 2 is a protein that specifically binds to vasopressin.

AVP is also known as ADH, ARVP, AVP-NPII, AVRP, VP.

Associated Diseases

• Diabetes insipidus, Neurohypophyseal type
• Hereditary arginine vasopressin deficiency
• Arginine vasopressin deficiency