AVIL
Description
The AVIL gene, also known as ‘Actin Binding Protein, Villin-like‘, plays a vital role in the organization and regulation of the actin cytoskeleton, a complex network of protein filaments essential for cell shape, movement, and intracellular transport. It is expressed in various tissues, including the brain, heart, and muscle, and its protein product, AVIL, interacts with other proteins to control actin filament dynamics. AVIL‘s intricate role in cytoskeletal function makes it crucial for various cellular processes, including cell division, migration, and signal transduction.
Associated Diseases
- Cancer (specifically colorectal and breast cancer)
- Neurological disorders (including Alzheimer‘s disease and Parkinson‘s disease)
- Heart disease
- Muscle disorders (such as muscular dystrophy)
Did you know?
AVIL is particularly abundant in the intestinal brush border, a specialized region of the gut lining responsible for nutrient absorption.
