ANO6


Description

The ANO6 (anoctamin 6) is a protein-coding gene located on chromosome 12.

ANO6 acts as a regulator of phospholipid scrambling in platelets and osteoblasts, a process essential for blood clotting and bone mineralization respectively. This activity is calcium-dependent and scrambles phosphatidylserine, phosphatidylcholine, and galactosylceramide. ANO6 can also generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes.

ANO6 is also known as BDPLT7, SCTS, TMEM16F.

Associated Diseases


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