AMBN
Description
The AMBN gene, also known as ameloblastin, is a crucial regulator of bone development and growth. It encodes a protein that plays a vital role in the formation of the enamel matrix, the outer layer of teeth. This protein interacts with other proteins involved in bone formation, influencing the differentiation and mineralization of osteoblasts, the cells responsible for bone growth. Mutations in the AMBN gene can lead to various bone-related disorders, highlighting its significant impact on skeletal health.
Associated Diseases
Did you know?
The AMBN gene is expressed not only in teeth but also in bone, cartilage, and other tissues, suggesting its broader role in connective tissue development.
