ALDH5A1 : aldehyde dehydrogenase 5 family member A1
Description
The ALDH5A1 (aldehyde dehydrogenase 5 family member A1) is a protein-coding gene located on chromosome 6.
The ALDH5A1 gene provides instructions for producing the succinic semialdehyde dehydrogenase enzyme. This enzyme is found in the mitochondria, which are the energy-producing centers of cells. Succinic semialdehyde dehydrogenase plays a role in the breakdown of gamma-amino butyric acid (GABA), a neurotransmitter that helps regulate brain activity. GABA prevents the brain from being overloaded with signals, and once it is released from nerve cells, it is broken down by succinic semialdehyde dehydrogenase and other enzymes.
Catalyzes the breakdown of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
ALDH5A1 is also known as SSADH, SSDH.
