AGPAT2 : 1-acylglycerol-3-phosphate O-acyltransferase 2
Description
AGPAT2, also known as 1-acylglycerol-3-phosphate O-acyltransferase 2, is a gene encoding an enzyme crucial for lipid metabolism. It catalyzes the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a key intermediate in the synthesis of triglycerides, phospholipids, and other essential lipids. AGPAT2 plays a vital role in regulating the composition and distribution of lipids in various tissues, including the liver, adipose tissue, and brain. Mutations in AGPAT2 can lead to a range of metabolic disorders, highlighting its importance in maintaining overall health.
Associated Diseases
Did you know?
AGPAT2 activity is regulated by various factors, including dietary fatty acid intake, insulin signaling, and hormones like leptin.
