AGA : aspartylglucosaminidase
Description
The AGA gene, also known as the androgen receptor gene, plays a crucial role in hair growth and development. It encodes a protein that binds to androgens, male sex hormones like testosterone, triggering a signaling cascade that influences hair follicle activity. This gene's function is intricately tied to hair follicle cycling, influencing the growth, resting, and shedding phases. Mutations or variations in the AGA gene can lead to hair loss disorders, highlighting its significant role in maintaining a healthy scalp and hair.
Associated Diseases
- Androgenetic alopecia (male-pattern baldness)
- Female pattern hair loss
- Alopecia areata
- Hirsutism (excessive hair growth in women)
Did you know?
The AGA gene is highly polymorphic, meaning it exhibits significant variation among individuals, contributing to the diverse hair traits observed in the human population.
