PPY
Description
The PPY (pancreatic polypeptide) is a protein-coding gene located on chromosome 17.
Pancreatic polypeptide (PPY) is a hormone secreted by pancreatic cells that plays a regulatory role in pancreatic and gastrointestinal functions. It likely achieves this by signaling through the G protein-coupled receptor NPY4R2.
PPY is also known as PH, PNP, PP.
Associated Diseases
- hyperinsulinism due to INSR deficiency
- hyperinsulinism due to glucokinase deficiency
- exercise-induced hyperinsulinism
- rectal neuroendocrine tumor G1
- multiple endocrine neoplasia type 1
- type 1 diabetes mellitus
- malignant endocrine neoplasm
- diabetic autonomic neuropathy
- autonomic neuropathy