PPRC1


Description

The PPRC1 (PPARG related coactivator 1) is a protein-coding gene located on chromosome 10.

PPRC1 (Peroxisome proliferator-activated receptor gamma coactivator-related protein 1) is a protein encoded by the PPRC1 gene in humans. It shares similarities with PPARGC1 (PPAR-gamma coactivator 1/PGC-1), a protein that activates mitochondrial biogenesis by interacting with nuclear respiratory factor 1 (NRF1). PPRC1 also interacts with NRF1, suggesting it may be a functional counterpart of PPARGC1, activating mitochondrial biogenesis via NRF1 in response to growth signals. PPRC1 has also been shown to interact with USF2.

PPRC1 is also known as PRC.

Associated Diseases



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